Description

L-Asparagine, N2-(Hydroxymethyl)- (9Ci) is a chemically modified derivative of the amino acid L-asparagine, featuring a hydroxymethyl group on the amide nitrogen. This functionalization makes it a valuable building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for compounds requiring modified amino acid backbones.
• Peptide Chemistry: Used in the synthesis of modified peptides and peptidomimetics, where the N-hydroxymethyl group can introduce specific reactivity or stability profiles.
• Bioconjugation & Linker Chemistry: Acts as a versatile spacer or linker molecule in bioconjugation strategies for attaching drugs, labels, or other functional groups to biomolecules.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, or plant growth regulators that incorporate amino acid derivatives.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways involving asparagine or glutamine.
• Material Science: Potential application as a monomer or modifying agent in the synthesis of specialized polymers with unique properties.

Basic Information

Product Name	L-Asparagine, N2-(Hydroxymethyl)- (9Ci)
CAS No.	73903-62-5
Molecular Formula	C5H10N2O4
Molecular Weight	162.15 g/mol
Synonyms	N-(Hydroxymethyl)-L-asparagine; L-Asparagine, N-(hydroxymethyl)-; (S)-2-Amino-3-carbamoylpropanoic acid N-(hydroxymethyl)-; N2-(Hydroxymethyl)-L-asparagine; N-Hydroxymethylasparagine; (2S)-2-Amino-4-carbamoylbutanoic acid N-(hydroxymethyl)amide
EINECS	Contact for details

Quality Control

Our L-Asparagine, N2-(Hydroxymethyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters such as assay (HPLC), chiral purity, and impurity profiles. For research and development purposes, we offer material in standard high-purity grades, with the capability to supply custom grades meeting specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% (L-Isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.