Description

n-Palmitoylglutamic Acid α-Methyl Ester is a high-purity synthetic derivative of glutamic acid, specifically engineered for advanced formulation chemistry. This compound is valued for its role as a key intermediate in the synthesis of specialized surfactants, emulsifiers, and active pharmaceutical ingredients (APIs). It is primarily utilized by manufacturers in the personal care, cosmetics, and pharmaceutical industries seeking to develop products with enhanced stability, skin compatibility, and functional performance.

Application

• Cosmetic & Personal Care Ingredient: Acts as a key intermediate for synthesizing high-performance, mild surfactants and emulsifiers used in facial cleansers, shampoos, and moisturizers.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) requiring specific lipophilic properties.
• Bioconjugation & Peptide Chemistry: Used in the modification of peptides and proteins to alter their solubility, stability, or targeting characteristics for research and therapeutic applications.
• Specialty Surfactant Production: A precursor for manufacturing novel anionic and amphoteric surfactants with tailored properties for industrial and specialty cleaning formulations.
• Lipid-Based Drug Delivery Systems: Incorporated into the design of lipid nanoparticles (LNPs) and other advanced delivery vehicles to improve drug encapsulation and bioavailability.
• Biodegradable Polymer Synthesis: Utilized as a monomer or co-monomer in the development of biodegradable polymers for medical and environmental applications.

Basic Information

Product Name	n-Palmitoylglutamic Acid α-Methyl Ester
CAS No.	73793-91-6
Molecular Formula	C₂₂H₄₁NO₅
Molecular Weight	399.57 g/mol
Synonyms	Palmitoyl-L-glutamic acid α-methyl ester; L-Glutamic acid, N-(1-oxohexadecyl)-, 1-methyl ester; Methyl N-palmitoyl-L-glutamate; N-Hexadecanoyl-L-glutamic acid methyl ester; Palmitoylglutamic acid methyl ester; N-Palmitoyl-L-glutamic acid 1-methyl ester; (S)-1-Methoxy-1-oxo-5-(palmitoylamino)pentane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our n-Palmitoylglutamic Acid α-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and cosmetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.