Description

5-Isobutyl-5-(2-Methyl-2-Propenyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is a specialized sodium salt derivative of a barbituric acid analog, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive, stabilized platform for constructing complex heterocyclic frameworks, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: Core building block for the synthesis of novel barbiturate and thiobarbiturate analogs with potential central nervous system (CNS) activity.
• Agrochemical Research: Used in developing new active ingredients for crop protection agents, leveraging its heterocyclic structure.
• Fine Chemical Synthesis: Key precursor in multi-step organic syntheses for creating complex, high-value specialty chemicals.
• Academic & Institutional R&D: Employed in medicinal chemistry programs to explore new structure-activity relationships (SAR) within the pyrimidinedione class.
• Process Chemistry Development: Serves as a model compound for optimizing scale-up parameters for sodium salt formations and subsequent reactions.

Basic Information

Product Name	5-Isobutyl-5-(2-Methyl-2-Propenyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione
CAS No.	73681-11-5
Molecular Formula	C12H17N2NaO3
Molecular Weight	260.27 g/mol
Synonyms	5-Isobutyl-5-(2-methyl-2-propenyl)-2-sodiooxy-4,6(1H,5H)-pyrimidinedione; Sodium 5-isobutyl-5-(2-methylprop-2-en-1-yl)-2,4,6-trioxo-1,3-diazinane-2-ide; 5-Isobutyl-5-(2-methylallyl)barbituric acid sodium salt; Sodium 5-isobutyl-5-(2-methylallyl)barbiturate; 2-Sodiooxy-5-isobutyl-5-(2-methyl-2-propenyl)-4,6-pyrimidinedione; 73681-11-5; Barbituric acid derivative, sodium salt
EINECS	Contact for details

Quality Control

Our 5-Isobutyl-5-(2-Methyl-2-Propenyl)-2-Sodiooxy-4,6(1H,5H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay (by HPLC), related substances, residual solvents, and moisture content. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.