Description

5-Ethyl-5-(2-Methylbutyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione is a specialized thiobarbiturate derivative, a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its value lies in its precise chemical structure, which is critical for producing compounds with specific pharmacological activity. This product is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of barbiturate analogs and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of thiobarbiturate-based active pharmaceutical ingredients (APIs).
• Research & Development: A crucial reagent in medicinal chemistry for developing new barbiturate and CNS-targeting drug candidates.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce the thiobarbiturate moiety into complex molecules.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-Ethyl-5-(2-Methylbutyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione
CAS No.	73681-03-5
Molecular Formula	C11H17N2NaO2S
Molecular Weight	264.32 g/mol
Synonyms	5-Ethyl-5-(2-methylbutyl)-2-thiobarbituric acid sodium salt; Sodium 5-ethyl-5-(2-methylbutyl)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione; 2-Thiobarbituric acid, 5-ethyl-5-(2-methylbutyl)-, sodium salt; Sodium 5-ethyl-5-(2-methylbutyl)-2-thiobarbiturate; Thiobarbiturate sodium salt derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(2-Methylbutyl)-2-Sodiothio-4,6(1H,5H)-Pyrimidinedione is manufactured under a quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the specifications required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.