Description

L-Glutamic Acid, n-[n-[n-[n-[4-[[(2, 4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-.Gamma.-Gluta Myl]-L-.Gamma.-Glutamyl]-L-.Gamma.-Glutamyl]- is a complex, high-purity folate derivative with a polyglutamyl tail, offering enhanced biochemical utility compared to simpler folate forms. This compound is critical for advanced research and development in biochemistry and pharmaceutical sciences, where precise molecular structure and activity are paramount. It is primarily sought by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in metabolic studies, enzyme research, and the synthesis of specialized biochemical reagents.

Application

• Biochemical Research: Used as a high-specificity substrate or inhibitor in enzymatic studies, particularly those involving folate-dependent enzymes and one-carbon metabolism pathways.
• Pharmaceutical Reference Standard: Serves as a critical analytical standard for the quality control and development of folate-based pharmaceuticals and nutraceuticals.
• Metabolic Pathway Analysis: Employed in cell culture and in vitro studies to investigate the role of polyglutamylated folates in cellular processes.
• Specialty Reagent Synthesis: Acts as a key intermediate or building block for the synthesis of more complex, labeled, or conjugated folate molecules for diagnostic and research applications.
• Nutritional Science Research: Utilized in studies aiming to understand the bioavailability and metabolism of complex dietary folates.

Basic Information

Product Name	L-Glutamic Acid, n-[n-[n-[n-[4-[[(2, 4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-.Gamma.-Gluta Myl]-L-.Gamma.-Glutamyl]-L-.Gamma.-Glutamyl]-
CAS No.	73610-81-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Pteroylpentaglutamic Acid; Folate Pentaglutamate; Vitamin B9 Pentaglutamate; PGA5; 5-Glutamyl Pteroylpoly-γ-glutamate; Tetrahydrofolylpentaglutamate (potential derivative); N-[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamyl-L-γ-glutamic Acid
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid, n-[n-[n-[n-[4-[[(2, 4-Diamino-6-Pteridinyl)Methyl]Methylamino]Benzoyl]-L-.Gamma.-Gluta Myl]-L-.Gamma.-Glutamyl]-L-.Gamma.-Glutamyl]- is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.