Description

Vasopressin, n-Acetyl-o-Methyl-Tyr(2)-Arg(8)- is a synthetic, modified peptide analog of the endogenous hormone vasopressin. This compound is engineered for enhanced receptor selectivity and metabolic stability, making it a critical tool for advanced biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroendocrinology, cardiovascular function, and renal physiology.

Application

• Pharmacological Research: Used as a selective ligand to study vasopressin receptor subtypes (V1a, V1b, V2) and their signaling pathways.
• Biochemical Assay Development: Serves as a reference standard or active component in high-throughput screening (HTS) and binding assays.
• Structure-Activity Relationship (SAR) Studies: A key molecule for investigating the impact of specific amino acid modifications on peptide hormone activity and stability.
• Preclinical Studies: Employed in animal models to investigate the physiological roles of vasopressin in blood pressure regulation, water balance, and social behavior.
• Peptide Chemistry Reference: Used as a building block or intermediate in the synthesis of more complex peptide conjugates and drug candidates.

Basic Information

Item	Detail
Product Name	Vasopressin, n-Acetyl-o-Methyl-Tyr(2)-Arg(8)-
CAS No.	73609-49-1
Molecular Formula	C48H68N14O12S2
Molecular Weight	1065.3 g/mol
Synonyms	[Arg8]-Vasopressin, N-Acetyl-O-methyl-Tyr(2)-; [Arg8]-Vasopressin, N-Acetyl-O-methyl-Tyr(2)-; Acetyl-O-methyl-Tyr(2)-Arg8-vasopressin; AVP (2-O-methyl-Tyr, N-Acetyl, 8-Arg); Modified Argipressin; d(CH2)5[Tyr(Me)2, Arg8]Vasopressin derivative
EINECS	Contact for details

Quality Control

Our Vasopressin, n-Acetyl-o-Methyl-Tyr(2)-Arg(8)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.