Description

Physalaemin, Lys(5)-Thr(6)- is a synthetic peptide analog of the naturally occurring tachykinin peptide, physalaemin. This compound is of significant interest in biochemical and pharmacological research due to its potent biological activity as a neurokinin receptor agonist. It is primarily utilized by research institutions and pharmaceutical development teams focused on neuroscience, inflammation, and pain pathway studies. The product is supplied as a high-purity material suitable for critical laboratory applications.

Application

• Neuroscience Research: Used as a selective agonist for neurokinin receptors (NK1, NK2) to study neuronal signaling, synaptic transmission, and neurogenic inflammation.
• Pharmacological Assays: Serves as a reference standard and active agent in in vitro and in vivo assays to evaluate receptor binding affinity and functional responses.
• Pain and Inflammation Studies: Applied in research models to investigate the role of tachykinins in nociception (pain perception) and inflammatory processes.
• Respiratory Research: Utilized in studies examining bronchoconstriction and airway hyperresponsiveness related to tachykinin pathways.
• Biochemical Tool Compound: Acts as a critical reagent for calibrating equipment, validating methods, and controlling experiments in peptide research.
• Drug Discovery & Development: Provides a structural template for the design and screening of novel therapeutic agents targeting neurokinin receptors.

Basic Information

Product Name	Physalaemin, Lys(5)-Thr(6)-
CAS No.	73572-30-2
Molecular Formula	C58H85N15O14S
Molecular Weight	1240.45 g/mol
Synonyms	[Lys5, Thr6]-Physalaemin; Lys5-Thr6-Physalaemin; Physalaemin (5-Lysine, 6-Threonine); H-Pyr-Ala-Asp-Pro-Asn-Lys-Phe-Tyr-Gly-Leu-Met-NH2; Tachykinin peptide analog; Neurokinin receptor agonist; NK1 receptor agonist
EINECS	Contact for details

Quality Control

Our Physalaemin, Lys(5)-Thr(6)- is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing specifications such as assay purity, peptide content, and impurity profiles. We adhere to stringent quality management practices suitable for research-grade biochemicals. Certificates of Analysis are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.