Description

Poly-Dl-Lysine Hydrobromide is a synthetic polyamino acid salt, widely utilized as a cationic coating agent to promote cell adhesion on various substrates. Its value lies in its ability to create a uniform, positively charged surface that enhances the attachment and growth of a broad range of cell types, including primary and stem cells. This makes it an essential reagent for researchers and manufacturers in life sciences, particularly for cell culture, microscopy, and biomedical device coating applications.

Application

• Cell Culture Substrate Coating: Essential for preparing glass slides, coverslips, and multi-well plates to improve the attachment and spreading of anchorage-dependent cells.
• Biomedical Research: Used in neuroscience, immunology, and cancer research to facilitate the study of cell behavior, proliferation, and differentiation.
• Tissue Engineering Scaffolds: Acts as a foundational layer to enhance the biocompatibility and cell-seeding efficiency of synthetic or natural scaffolds.
• Diagnostic Assays: Employed to immobilize cells or biomolecules on sensor surfaces for diagnostic and biosensing applications.
• Microscopy and Imaging: Provides a stable, non-fluorescent background for high-resolution imaging techniques like fluorescence and confocal microscopy.
• Virology Studies: Used to coat surfaces for viral plaque assays and other virological techniques requiring adherent cell monolayers.

Basic Information

Product Name	Poly-Dl-Lysine Hydrobromide
CAS No.	73565-55-6
Molecular Formula	(C6H14N2O2 • HBr)n
Molecular Weight	Varies by chain length (monomer unit: 229.10 g/mol)
Synonyms	PDL-HBr; Poly(DL-lysine hydrobromide); Poly-L-lysine hydrobromide (DL-form); PLL-HBr; Poly(lysine) hydrobromide; DL-Polylysine hydrobromide; NSC 106982; Poly(amino acid) coating reagent
EINECS	Contact for details

Quality Control

Our Poly-Dl-Lysine Hydrobromide is manufactured under controlled conditions to ensure batch-to-batch consistency and performance. Each lot undergoes rigorous analytical testing, including assessment of molecular weight distribution, purity, and biological activity for cell adhesion. Certificates of Analysis (COA) detailing specific test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (Nitrogen)	≥ 95.0%
Molecular Weight Range	30,000 - 70,000 Da (Typical)
Loss on Drying	≤ 5.0 %
Biological Activity (Cell Adhesion)	Pass
Endotoxin Level	< 1.0 EU/mg (for cell culture grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.