Description

(D-Trp2)-Methionine Enkephalinamide*Acet Ate CAS NO 73459-29-7 is a synthetic peptide analog of the endogenous opioid peptide methionine-enkephalin, modified with a D-tryptophan residue at position 2. This modification enhances its metabolic stability and receptor selectivity, making it a critical tool for advanced neuropharmacological research. It is primarily utilized by pharmaceutical R&D teams and academic researchers studying opioid receptor mechanisms, pain pathways, and the development of novel therapeutic agents.

Application

• Neuroscience Research: As a selective ligand for probing delta and mu opioid receptor subtypes in binding assays and functional studies.
• Pharmacology Development: Serving as a reference standard or lead compound in the design of new analgesic drugs with improved stability profiles.
• Biochemical Assays: Used in enzyme inhibition studies and signal transduction pathway analysis related to opioid systems.
• Cell Culture Studies: Application in vitro to study the effects of opioid receptor activation on cellular responses and gene expression.
• Academic & Institutional Research: A key reagent for university and government labs conducting fundamental research on neuropeptides and their analogs.

Basic Information

Product Name	(D-Trp2)-Methionine Enkephalinamide*Acet Ate
CAS No.	73459-29-7
Molecular Formula	C37H48N8O7S • C2H4O2
Molecular Weight	792.94 g/mol
Synonyms	(D-Trp2)-Met-Enkephalinamide acetate salt; [D-Trp2]-Met-Enkephalinamide acetate; Tyr-D-Trp-Gly-Phe-Met-NH2 acetate; D-Tryptophan(2)-methionine enkephalinamide acetate; Opioid peptide analog 73459-29-7; H-Tyr-D-Trp-Gly-Phe-Met-NH2 • AcOH; ENK-D-Trp2 amide acetate
EINECS	Contact for details

Quality Control

Our (D-Trp2)-Methionine Enkephalinamide*Acet Ate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing purity, solvent content, and other critical parameters to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC/Titration)	Conforms
Peptide Content (Amino Acid Analysis)	≥ 70.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.