Description

n-α-Carbobenzoxy-3-Methoxy-Ortho-Methyl- L-Tyrosine is a protected, non-natural amino acid derivative primarily used as a sophisticated building block in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide structure and function, particularly in the development of novel therapeutic agents. It is essential for pharmaceutical R&D, especially in the synthesis of complex peptides and peptidomimetics where specific side-chain protection and modification are required. The product is supplied to meet the stringent quality demands of the global life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used to introduce modified tyrosine analogs into peptide chains to study structure-activity relationships (SAR) and enhance metabolic stability.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or affinity probes used in biochemical and diagnostic applications.
• Academic & Industrial R&D: Employed in research laboratories for developing new synthetic methodologies and exploring new chemical entities.
• Custom Peptide Synthesis: Utilized by CROs and CDMOs for the contract manufacturing of bespoke peptides for clients in drug discovery.

Basic Information

Item	Detail
Product Name	n-α-Carbobenzoxy-3-Methoxy-Ortho-Methyl- L-Tyrosine
CAS No.	73404-23-6
Molecular Formula	C20H23NO6
Molecular Weight	373.40 g/mol
Synonyms	Z-3-Methoxy-2-methyl-L-tyrosine; Cbz-3-OMe-2-Me-L-Tyr-OH; N-Carbobenzoxy-3-methoxy-2-methyl-L-tyrosine; (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(3-methoxy-2-methylphenyl)propanoic acid; Z-L-Tyr(3-OMe,2-Me)-OH; Nα-Z-3-Methoxy-ortho-methyl-L-tyrosine; Benzyl N-[(1S)-1-carboxy-2-(3-methoxy-2-methylphenyl)ethyl]carbamate
EINECS	Contact for details

Quality Control

Every batch of n-α-Carbobenzoxy-3-Methoxy-Ortho-Methyl- L-Tyrosine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.