Description

Msh, (2-Phe-4-Nle)α- is a synthetic peptide analog of α-melanocyte-stimulating hormone (α-MSH). This compound is significant for its role in melanogenesis research and as a key intermediate in the development of peptide-based therapeutics and diagnostic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology, dermatology, and pigment biology.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of melanocortin receptors (MC1R), skin pigmentation, and inflammation pathways.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of novel peptide drugs targeting metabolic disorders, sexual dysfunction, and anti-inflammatory responses.
• Diagnostic Tool Development: Employed in the creation of assays and imaging probes to study receptor distribution and function in vitro and in vivo.
• Cosmeceutical Research: Investigated for potential applications in skin care formulations aimed at modulating pigmentation.
• Academic & Institutional Studies: Utilized in university and research institute labs for fundamental studies in peptide chemistry, hormone action, and signal transduction.

Basic Information

Product Name	Msh, (2-Phe-4-Nle)α-
CAS No.	73391-90-9
Molecular Formula	C78H111N21O19S
Molecular Weight	1666.9 g/mol
Synonyms	α-MSH (2-Phe-4-Nle) analog; [Phe2, Nle4]-α-MSH; Ac-Ser-Tyr-Ser-Phe-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2; Melanotan I (MT-I); [Nle4, D-Phe7]-α-MSH; Afamelanotide analog; NDP-MSH analog; Melanocyte-Stimulating Hormone analog
EINECS	Contact for details

Quality Control

Our Msh, (2-Phe-4-Nle)α- is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and residual solvent levels are provided to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.