Description

n-(tert-Butoxycarbonyl)-L-Tyrosyl-D-Methionylglycyl-4-Nitro-3-Phenyl-L-Alanyl-L-Prolinamide CAS NO 73385-91-8 is a complex, Boc-protected pentapeptide derivative designed for advanced research and development. This compound is of significant value as a key synthetic intermediate or a reference standard in the development of novel peptide-based therapeutics and biochemical probes. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on peptide chemistry, drug discovery, and proteomics.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the solid-phase or solution-phase synthesis of complex peptide drug candidates.
• Biochemical Research: Used as a reference standard or substrate in enzymatic studies, receptor binding assays, and structure-activity relationship (SAR) investigations.
• Protease Inhibitor Development: Acts as a potential precursor or model compound for designing inhibitors targeting specific proteolytic enzymes.
• Peptide Library Construction: Employed in the generation of focused peptide libraries for high-throughput screening in drug discovery programs.
• Academic Research: Utilized in university and institutional labs for teaching advanced peptide synthesis techniques and studying peptide conformation and stability.

Basic Information

Product Name	n-(tert-Butoxycarbonyl)-L-Tyrosyl-D-Methionylglycyl-4-Nitro-3-Phenyl-L-Alanyl-L-Prolinamide
CAS No.	73385-91-8
Molecular Formula	C₃₇H₅₀N₈O₁₀S
Molecular Weight	814.91 g/mol
Synonyms	Boc-Tyr-D-Met-Gly-(4-NO₂-3-Phe)-Ala-Pro-NH₂; Boc-L-Tyrosyl-D-Methionylglycyl-4-Nitro-3-Phenyl-L-Alanyl-L-Prolinamide; 73385-91-8; Pentapeptide Derivative Boc-Tyr-D-Met-Gly-(4-Nitro-3-Phenyl-Ala)-Ala-Pro-NH₂; t-Butoxycarbonyl-Tyr-D-Met-Gly-(4-Nitro-Phe(3))-Ala-Pro Amide; (S)-2-((S)-2-((R)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-(4-hydroxyphenyl)propanamido)-4-(methylthio)butanamido)acetamido)-3-(4-nitro-3-phenylphenyl)propanamido)pyrrolidine-1-carboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of n-(tert-Butoxycarbonyl)-L-Tyrosyl-D-Methionylglycyl-4-Nitro-3-Phenyl-L-Alanyl-L-Prolinamide is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere at lower temperatures (e.g., -20°C).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.