Description

Vasopressin, Val-Asp-Arg(8)- CAS NO 73303-58-9 is a synthetic analogue of the endogenous neurohypophysial hormone arginine vasopressin, characterized by specific amino acid substitutions. This compound is of significant interest for its potent and selective pharmacological activity, primarily as a V1a receptor agonist. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors who require high-purity peptide standards for advanced drug discovery, metabolic studies, and the development of novel therapeutic agents targeting vasopressin pathways.

Application

• Pharmaceutical Research & Development: As a critical reference standard and active pharmaceutical ingredient (API) in the development of drugs targeting cardiovascular, renal, and central nervous system disorders.
• Biochemical Assay Development: For use in receptor binding studies, functional cell-based assays, and high-throughput screening to evaluate V1a receptor activity and selectivity.
• Metabolic Pathway Studies: As a tool compound to investigate the role of vasopressin and its analogues in water homeostasis, blood pressure regulation, and stress response.
• Peptide Chemistry & Synthesis: Serves as a benchmark molecule for method development in solid-phase peptide synthesis (SPPS), purification, and analytical characterization.
• Academic & Clinical Research: Used in university and institutional labs for fundamental research into endocrinology, neurobiology, and related physiological processes.

Basic Information

Product Name	Vasopressin, Val-Asp-Arg(8)-
CAS No.	73303-58-9
Molecular Formula	C46H65N13O12S2
Molecular Weight	1048.2 g/mol
Synonyms	[1-(L-Mercaptopropionic acid), 2-(O-methyl-L-tyrosine), 4-L-valine, 8-L-arginine]vasopressin; [Val4, D-Arg8]Vasopressin; dVDAVP; Desmopressin analogue; VDAVP; 1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-4-L-valine-8-L-arginine-vasopressin; (Val4, Arg8)-Vasopressin
EINECS	Contact for details

Quality Control

Our Vasopressin, Val-Asp-Arg(8)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis, to ensure it meets exacting standards for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.