Description

D-Sultopride is a high-purity, enantiomerically pure benzamide derivative with significant pharmacological interest. This compound serves as a critical chiral intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis and study of dopamine receptor antagonists, particularly for central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of novel antipsychotic and neuroleptic drug candidates.
• Biochemical Research: Used as a selective ligand in receptor binding assays to study dopamine D2 and D3 receptor subtypes.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Metabolite Studies: Employed in the research of drug metabolism and pharmacokinetics (DMPK) for related benzamide drugs.
• Process Chemistry: Utilized in route scouting and optimization for the commercial-scale production of sultopride and its analogs.

Basic Information

Product Name	D-Sultopride
CAS No.	73294-92-5
Molecular Formula	C15H23N3O4S
Molecular Weight	341.43 g/mol
Synonyms	(R)-Sultopride; Dextro-Sultopride; (R)-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide; (R)-5-(Ethylsulfonyl)-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide; D(-)-Sultopride; (2R)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide; UNII-7X3I6D5J1H; Benzamide, 5-(ethylsulfonyl)-2-methoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-, (R)-
EINECS	Contact for details

Quality Control

Our D-Sultopride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the hygroscopic material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-Enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.