Description

5-(2-Ppropenylthio)-2,4(1H,3H)-Pyrimidinedione is a specialized thiopyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique sulfur-containing pyrimidine core enables specific molecular interactions. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel nucleoside analogs and other potential antiviral or anticancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the pyrimidine scaffold.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex sulfur- and nitrogen-containing heterocycles for material science and specialty chemistry.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a molecular probe due to its structural similarity to natural pyrimidine bases.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	5-(2-Ppropenylthio)-2,4(1H,3H)-Pyrimidinedione
CAS No.	73236-43-8
Molecular Formula	C7H8N2O2S
Molecular Weight	184.21 g/mol
Synonyms	5-(Allylthio)uracil; 5-Allylmercaptouracil; 2,4-Dihydroxy-5-(allylthio)pyrimidine; 5-(2-Propen-1-ylthio)-2,4(1H,3H)-pyrimidinedione; Allylthiouracil; NSC 163049; Uracil, 5-(allylthio)-; 5-ALLYLTHIO-2,4-DIHYDROXYPYRIMIDINE
EINECS	Contact for details

Quality Control

Our 5-(2-Ppropenylthio)-2,4(1H,3H)-Pyrimidinedione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring material that meets stringent internal standards and can align with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.