Description

Somatostatin, Phe(4)- CAS NO 73107-31-0 is a synthetic analogue of the endogenous peptide hormone somatostatin, specifically modified with a phenylalanine substitution at position 4. This modification is designed to enhance its stability and receptor-binding affinity for targeted research and development applications. It is a critical compound for pharmaceutical researchers and developers working on metabolic disorders, oncology, and advanced peptide therapeutics.

Application

• Pharmaceutical R&D: Used as a reference standard and active pharmaceutical ingredient (API) in the development of novel somatostatin receptor-targeting drugs.
• Endocrinology Research: A key tool for studying the inhibition of growth hormone, insulin, and glucagon secretion in metabolic disease models.
• Oncology Research: Investigated for its potential anti-proliferative effects on certain cancer cell lines expressing somatostatin receptors.
• Peptide Chemistry Studies: Serves as a model compound for studying structure-activity relationships (SAR) and peptide stability.
• Biochemical Assay Development: Utilized in the development and validation of high-throughput screening (HTS) assays and receptor binding studies.

Basic Information

Product Name	Somatostatin, Phe(4)-
CAS No.	73107-31-0
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	Phe(4)-Somatostatin; Somatostatin (4-Phenylalanine); H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (cyclic 3-14 disulfide); SRIF analogue; SMS 201-995 analogue (partial); Lanreotide precursor analogue; Cyclic somatostatin tetradecapeptide analogue
EINECS	Contact for details

Quality Control

Our Somatostatin, Phe(4)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.