Description

D-A-Aminoxy-B-Phenylpropionic Acid, Hydrobromide is a high-purity, non-natural amino acid derivative used as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily required by research institutions and pharmaceutical companies engaged in peptide mimetic design, medicinal chemistry, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptidomimetics & Constrained Peptides: Used to introduce the unique aminoxy functionality into peptide backbones, enhancing metabolic stability and modulating biological activity.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship studies to explore novel chemical space and optimize drug candidate properties.
• Bioconjugation & Linker Chemistry: Serves as a specialized building block for creating cleavable linkers in antibody-drug conjugates (ADCs) and other targeted therapies.
• Chemical Biology Probes: Integral in the synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or precursor in catalytic asymmetric reactions to access enantiomerically pure compounds.

Basic Information

Product Name	D-A-Aminoxy-B-Phenylpropionic Acid, Hydrobromide
CAS No.	73086-98-3
Molecular Formula	C9H12BrNO3
Molecular Weight	262.10 g/mol
Synonyms	(R)-2-Aminooxy-3-phenylpropanoic acid hydrobromide; D-2-Aminooxy-3-phenylpropionic acid HBr; (R)-2-(Aminooxy)-3-phenylpropanoic acid hydrobromide; D-α-Aminoxy-β-phenylpropionic acid hydrobromide; (R)-AOPP.HBr; D-AOPP.HBr; (2R)-2-(Aminooxy)-3-phenylpropanoic acid hydrobromide
EINECS	Contact for details

Quality Control

Our D-A-Aminoxy-B-Phenylproponic Acid, Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports applications in cGMP and non-GMP research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.