Description

1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-2-(1,3-Dithian-2-Yl)Pyr Imidin-4-One is a specialized nucleoside analogue with a unique dithiane-protected structure, making it a valuable intermediate in advanced synthetic chemistry. This compound matters for its role in the precise construction of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active ingredients and prodrugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogues.
• Prodrug Development: Used in research to create masked or protected forms of active pharmaceutical ingredients (APIs) to improve bioavailability or stability.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides with specific mode-of-action targets.
• Biochemical Research: Tool compound for studying enzyme mechanisms, particularly those involving nucleotide metabolism and processing.
• Fine Chemical Manufacturing: Serves as a precursor for high-value, complex specialty chemicals used in various industrial applications.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-2-(1,3-Dithian-2-Yl)Pyr Imidin-4-One
CAS No.	73080-24-7
Molecular Formula	C13H18N2O6S2
Molecular Weight	362.42 g/mol
Synonyms	2-(1,3-Dithian-2-yl)-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-4-one; 2-(1,3-Dithian-2-yl)-1-β-D-ribofuranosylpyrimidin-4(1H)-one; Dithiane-protected ribosyl pyrimidinone; 1-(β-D-Ribofuranosyl)-2-(1,3-dithian-2-yl)pyrimidin-4(1H)-one; Protected Nucleoside Intermediate; CAS 73080-24-7
EINECS	Contact for details

Quality Control

Our 1-[3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-2-(1,3-Dithian-2-Yl)Pyr Imidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.