Description

Chorionic Gonadotropin-Beta (109-145) (Human) is a synthetic peptide fragment corresponding to a specific region of the β-subunit of human chorionic gonadotropin (hCG). This high-purity reference standard is critical for research and development in endocrinology and reproductive biology. It is primarily utilized by pharmaceutical R&D teams, clinical diagnostics manufacturers, and academic research institutions for immunoassay development, antibody production, and metabolic studies.

Application

• Immunoassay Standard & Calibration: Serves as a precise reference material for the development and calibration of diagnostic immunoassays measuring hCG levels.
• Antibody Production & Characterization: Used as an immunogen or antigen for generating and screening monoclonal and polyclonal antibodies specific to the hCG β-subunit.
• Biochemical Research: A key tool for studying the structure, function, and receptor binding mechanisms of hCG and related glycoprotein hormones.
• Pharmaceutical Quality Control: Employed as a system suitability standard in the analytical testing of biopharmaceutical products related to fertility and hormone therapies.
• Clinical Study Reagent: Used in research settings to investigate hormonal pathways, tumor markers (e.g., certain cancers), and reproductive disorders.

Basic Information

Product Name	Chorionic Gonadotropin-Beta (109-145) (Human)
CAS No.	72979-70-5
Molecular Formula	C172H277N51O55S2
Molecular Weight	3975.5 g/mol
Synonyms	hCG-beta (109-145); Human Chorionic Gonadotropin Beta Chain Fragment 109-145; hCG β-subunit fragment (109-145); CG-beta (109-145); Chorionic Gonadotropin Beta Polypeptide Fragment; β-hCG (109-145); hCGβ (109-145); Pregnancy Hormone β-Subunit Fragment
EINECS	Contact for details

Quality Control

Our Chorionic Gonadotropin-Beta (109-145) (Human) is manufactured under strict quality systems. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry to ensure high purity and precise molecular identity. Certificates of Analysis (COA) providing full analytical data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Amino Acid Sequence	H-Cys-Ala-Pro-Leu-Arg-Pro-Ile-Asn-Ala-Thr-Leu-Ala-Val-Glu-Lys-Glu-Gly-Cys-Pro-Val-Cys-Ile-Thr-Val-Asn-Thr-Thr-Ile-Cys-Ala-Gly-Tyr-Cys-Arg-Thr-Thr-Asp-OH (Disulfide bridge: Cys110-Cys145)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.