Description

Cysteinyl-Leucyl-Glutamyl-Glutamyl-Prolyl-Cysteine Cyclic Disulfide is a synthetic peptide featuring a cyclic disulfide bridge, which confers structural stability and is critical for mimicking bioactive conformations. This compound is essential for advanced research in peptide chemistry and drug discovery, particularly for studying disulfide bond formation and protein folding. It serves as a valuable intermediate and reference standard for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing novel peptide-based therapeutics and diagnostic tools.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of complex peptide drugs and as a reference standard for analytical method development.
• Bioconjugation & Probe Development: Serves as a scaffold for creating fluorescent or affinity probes due to its reactive disulfide bond, useful in biochemical assays.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the role of specific amino acid sequences and disulfide bonds in peptide bioactivity and receptor binding.
• Enzyme Substrate & Inhibitor Design: Acts as a substrate or inhibitor model for proteases and other enzymes involved in peptide metabolism.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in peptide synthesis, folding, and stability.
• Biotechnology: Potential use in the development of biosensors or as a component in engineered protein constructs requiring specific cyclic motifs.

Basic Information

Product Name	Cysteinyl-Leucyl-Glutamyl-Glutamyl-Prolyl-Cysteine Cyclic Disulfide
CAS No.	72903-48-1
Molecular Formula	C27H42N6O11S2
Molecular Weight	690.8 g/mol
Synonyms	Cys-Leu-Glu-Glu-Pro-Cys Cyclic Disulfide; Cys-Leu-Glu-Glu-Pro-Cys (cyclic); Cys-Leu-Glu-Glu-Pro-Cys (1→6)-disulfide; Cys-Leu-Glu-Glu-Pro-Cys (1-6)-disulfide; Cys-Leu-Glu-Glu-Pro-Cys (1-6) disulfide; Cys-Leu-Glu-Glu-Pro-Cys (1→6) disulfide; Cys-Leu-Glu-Glu-Pro-Cys (1-6) cyclic disulfide; Cys-Leu-Glu-Glu-Pro-Cys (1→6) cyclic disulfide
EINECS	Contact for details

Quality Control

Our Cysteinyl-Leucyl-Glutamyl-Glutamyl-Prolyl-Cysteine Cyclic Disulfide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.