Description

Boc-Glu-Glu-Leu-OMe is a protected tripeptide derivative, a crucial building block in solid-phase peptide synthesis (SPPS). Its value lies in providing controlled chain elongation while preventing unwanted side reactions, ensuring high-purity peptide sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of longer, complex peptide-based drug candidates.
• Biochemical Research: Used in studies of peptide structure-activity relationships (SAR) and enzyme-substrate interactions.
• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the controlled, sequential addition of amino acids in automated peptide synthesizers.
• Antigen Synthesis: Employed in the production of specific peptide sequences for antibody generation and immunological assays.
• Protease Substrate Analog: Serves as a model compound for investigating the specificity and mechanism of proteolytic enzymes.
• Custom Peptide Service: A critical raw material for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide production.

Basic Information

Product Name	Boc-Glu-Glu-Leu-OMe
CAS No.	72903-33-4
Molecular Formula	C24H41N3O10
Molecular Weight	531.60 g/mol
Synonyms	Boc-Glu-Glu-Leu-OMe; tert-Butyloxycarbonyl-L-glutamyl-L-glutamyl-L-leucine methyl ester; N-(tert-Butoxycarbonyl)-L-glutamyl-L-glutamyl-L-leucine methyl ester; Boc-L-Glu-L-Glu-L-Leu-OMe; Boc-Glu(OtBu)-Glu(OtBu)-Leu-OMe; (3S,6S,9S)-3,6-Bis(4-(tert-butoxy)-4-oxobutyl)-9-isobutyl-1,4,7-trioxo-2,5,8-triazadecane-10-carboxylic acid methyl ester; Boc-EELeu-OMe
EINECS	Contact for details

Quality Control

Our Boc-Glu-Glu-Leu-OMe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. We provide Certificates of Analysis (COA) with detailed specifications to ensure the material meets the rigorous standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Optical Rotation	-30° to -35° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.