Description

6-o-(4-C-Methyl-3-Methylamino-3-Deoxy-β-L-Arabinopyranosyl)-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Erythro-Hexopyranosyl)-3-Amino-1,2,3-Trideoxy-D-Myo-Inositol is a structurally complex aminoglycoside derivative, representing a high-value synthetic intermediate or reference standard for advanced pharmaceutical research. Its intricate glycosidic architecture makes it a compound of significant interest for the development of novel therapeutic agents, particularly in the field of anti-infectives. This product is essential for research institutions and pharmaceutical companies focused on antibiotic mechanism studies, structure-activity relationship (SAR) investigations, and the synthesis of next-generation aminoglycoside analogs.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate or reference standard in the synthesis and study of novel aminoglycoside antibiotics.
• Mechanistic Studies: Used to investigate bacterial ribosome binding, antibiotic resistance mechanisms, and modes of action at the molecular level.
• Structure-Activity Relationship (SAR) Analysis: Provides a key scaffold for modifying functional groups to optimize antimicrobial potency and reduce ototoxicity/nephrotoxicity.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories (HPLC, LC-MS).
• Biochemical Research: Utilized in enzymatic studies related to glycosyltransferases and as a probe for specific biological pathways.
• Academic Research: A valuable compound for universities and institutes conducting cutting-edge research in medicinal chemistry and chemical biology.

Basic Information

Item	Details
Product Name	6-o-(4-C-Methyl-3-Methylamino-3-Deoxy-β-L-Arabinopyranosyl)-4-o-(2,6-Diamino-2,3,4,6-Tetradeoxy-α-D-Erythro-Hexopyranosyl)-3-Amino-1,2,3-Trideoxy-D-Myo-Inositol
CAS No.	72854-57-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Amino-1,2,3-trideoxy-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl)-D-myo-inositol; 3'-Deoxy-3'-methylaminokanamycin B; 3'-Deoxy-3'-methylamino-kanamycin B; 3'-Methylamino-3'-deoxykanamycin B; Antibiotic NK 1003; NK 1003; NK-1003; 3'-N-Methylkanamycin B
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture content. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with research-grade specifications. For cGMP or other specific regulatory requirements, please contact our technical team to discuss custom synthesis and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.