Description

5-Bromo-4-Thioxo-3,4-Dihydro-1H-Pyrimidin-2-One is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceutical intermediates and agrochemicals, particularly those targeting specific enzymatic pathways. Research and development teams in the pharmaceutical, agrochemical, and fine chemical industries require this high-purity intermediate to synthesize complex molecules for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its unique thioxo-pyrimidinone core.
• Chemical Research & Development: A valuable reagent for exploring new heterocyclic chemistry and creating libraries of compounds for high-throughput screening.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its functional groups.
• Bioconjugation Chemistry: The reactive sites can be utilized for modifying biomolecules in biochemical research applications.

Basic Information

Product Name	5-Bromo-4-Thioxo-3,4-Dihydro-1H-Pyrimidin-2-One
CAS No.	72812-45-4
Molecular Formula	C4H3BrN2OS
Molecular Weight	206.05 g/mol
Synonyms	5-Bromo-2-mercapto-4-pyrimidinol; 5-Bromo-4-pyrimidinol-2(1H)-thione; 5-Bromo-2-thioxo-1,2-dihydropyrimidin-4-ol; 5-Bromo-4-hydroxypyrimidine-2-thiol; 5-Bromo-2,4-dihydroxypyrimidine-2-thione (tautomer); 72812-45-4; 5-Bromo-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Thioxo-3,4-Dihydro-1H-Pyrimidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.