Description

L-5,5-Dimethylthiazolidine-4-Carboxylic Acid is a high-purity, specialized heterocyclic compound that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique thiazolidine carboxylic acid structure makes it valuable for constructing complex molecules with precise stereochemistry. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for applications requiring high enantiomeric purity and structural novelty.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in therapeutic areas targeting metabolic and neurological disorders.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: An intermediate in the production of advanced, stereospecific herbicides and fungicides.
• Bioconjugation and Probe Chemistry: Utilized in the creation of biochemical probes and for bioconjugation techniques due to its reactive carboxylic acid group and heterocyclic core.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and for exploring new chemical spaces in drug discovery programs.

Basic Information

Product Name	L-5,5-Dimethylthiazolidine-4-Carboxylic Acid
CAS No.	72778-00-8
Molecular Formula	C6H11NO2S
Molecular Weight	161.22 g/mol
Synonyms	L-5,5-Dimethyl-4-thiazolidinecarboxylic Acid; (4R)-5,5-Dimethyl-1,3-thiazolidine-4-carboxylic Acid; (R)-5,5-Dimethylthiazolidine-4-carboxylic Acid; DMTCA; L-DMTCA; (R)-DMTCA; 5,5-Dimethyl-L-thiazolidine-4-carboxylic Acid; L-2,2-Dimethylthiazolidine-4-carboxylic Acid (older nomenclature)
EINECS	Contact for details

Quality Control

Our L-5,5-Dimethylthiazolidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity (assay), enantiomeric excess, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.