Description

2-(Difluoromethoxy)Benzyl Alcohol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the difluoromethoxy and benzyl alcohol functional groups, enabling precise molecular modifications. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronics: Employed in the development of novel organic semiconductors and electronic materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol moiety can be utilized in protective group strategies during multi-step synthetic sequences.

Basic Information

Product Name	2-(Difluoromethoxy)Benzyl Alcohol
CAS No.	72768-94-6
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	2-(Difluoromethoxy)benzenemethanol; (2-(Difluoromethoxy)phenyl)methanol; Benzyl alcohol, 2-(difluoromethoxy)-; α-(Difluoromethoxy)-o-tolyl alcohol; o-(Difluoromethoxy)benzyl alcohol; 2-(Difluoromethoxy)phenylmethanol; DFMBA
EINECS	Contact for details

Quality Control

Our 2-(Difluoromethoxy)Benzyl Alcohol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.