Description

γ-Melanocyte Stimulating Hormone (γ-MSH) is a bioactive peptide fragment derived from proopiomelanocortin (POMC) with significant research and potential therapeutic interest. Its primary value lies in its role as a potent melanocortin receptor agonist, influencing a range of physiological processes from pigmentation to energy homeostasis. This high-purity peptide is essential for researchers in pharmaceutical development, academic biochemistry, and life science research focusing on endocrine signaling and receptor studies.

Application

• Biomedical Research: Used as a critical reference standard and tool compound for studying melanocortin receptor (MCR) subtypes, particularly MC3R.
• Pharmacology & Drug Discovery: Serves as a lead compound or benchmark in the development of novel therapeutics targeting metabolic disorders, inflammation, and cardiovascular functions.
• Endocrinology Studies: Fundamental for investigating the physiological roles of POMC-derived peptides in energy balance, feeding behavior, and neuroendocrine regulation.
• In Vitro & In Vivo Assays: Applied in cell-based assays and animal model studies to elucidate signaling pathways and biological effects of γ-MSH.
• Diagnostic Development: Potential use in the calibration of immunoassays designed to detect related hormones or metabolic markers.

Basic Information

Product Name	γ-Melanocyte Stimulating Hormone
CAS No.	72711-43-4
Molecular Formula	C₇₇H₁₀₉N₂₁O₁₉S
Molecular Weight	1644.9 g/mol
Synonyms	γ-MSH; γ-MSH; Melanotropin gamma; γ-Melanotropin; Pro-opiomelanocortin-derived peptide; Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-NH₂ (sequence for human γ₁-MSH); POMC (92-101) (human); Melanocyte-Stimulating Hormone gamma
EINECS	Contact for details

Quality Control

Our γ-Melanocyte Stimulating Hormone is manufactured under strict quality systems suitable for research applications. Each batch is characterized using advanced analytical techniques to ensure high purity and structural integrity. Our products undergo rigorous quality testing, and comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and analytical results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Conforms to theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.