Description

Acetamide, N-[6-Amino-1,2,3,4-tetrahydro-1-(2-hydroxypropyl)-3-methyl-2,4-dioxo-5-pyrimidinyl]- is a specialized heterocyclic acetamide derivative with a complex pyrimidine-dione core structure. This compound matters as a high-value pharmaceutical intermediate and research chemical for the development of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical synthesis industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside analogs and other active pharmaceutical ingredients (APIs) with potential antiviral or anticancer activity.
• Biochemical Research: Used as a precursor or reference standard in medicinal chemistry programs targeting enzyme inhibition, particularly those involving pyrimidine metabolism.
• Fine Chemical Synthesis: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in custom synthesis and contract manufacturing.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	Acetamide, N-[6-Amino-1,2,3,4-tetrahydro-1-(2-hydroxypropyl)-3-methyl-2,4-dioxo-5-pyrimidinyl]-
CAS No.	72702-67-1
Molecular Formula	C10H16N4O4
Molecular Weight	256.26 g/mol
Synonyms	5-Acetamido-1-(2-hydroxypropyl)-3-methylpyrimidine-2,4(1H,3H)-dione; 1-(2-Hydroxypropyl)-3-methyl-5-acetamidouracil; N-[6-Amino-1-(2-hydroxypropyl)-3-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl]acetamide; 5-Acetylamino-1-(2-hydroxypropyl)-3-methyluracil; Acetamide, N-[6-amino-1,2,3,4-tetrahydro-1-(2-hydroxypropyl)-3-methyl-2,4-dioxo-5-pyrimidinyl]- (9CI); Uracil derivative, 5-acetamido-1-(2-hydroxypropyl)-3-methyl-
EINECS	Contact for details

Quality Control

Our Acetamide, N-[6-Amino-1,2,3,4-tetrahydro-1-(2-hydroxypropyl)-3-methyl-2,4-dioxo-5-pyrimidinyl]- is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.