Description

6,8-Dichloro-4-Piperazin-1-Yl-Quinazoline is a high-value, synthetically versatile quinazoline derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in its functionalized heterocyclic structure, which is essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule therapeutic candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying enzyme function and cellular signaling processes.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects requiring complex, functionalized quinazoline scaffolds.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in heterocyclic chemistry and medicinal chemistry.

Basic Information

Product Name	6,8-Dichloro-4-Piperazin-1-Yl-Quinazoline
CAS No.	72700-41-5
Molecular Formula	C12H11Cl2N5
Molecular Weight	296.15 g/mol
Synonyms	4-(Piperazin-1-yl)-6,8-dichloroquinazoline; 6,8-Dichloro-4-(1-piperazinyl)quinazoline; 6,8-Dichloro-4-piperazinylquinazoline; Quinazoline, 6,8-dichloro-4-(1-piperazinyl)-; 72700-41-5; 6,8-Dichloro-4-piperazin-1-ylquinazoline
EINECS	Contact for details

Quality Control

Our 6,8-Dichloro-4-Piperazin-1-Yl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.