Description

Suc-Ala-Pro-Ala-Pna CAS NO 72682-79-2 is a specialized chromogenic peptide substrate designed for enzymatic research and assay development. This compound is of critical importance for the study of proteolytic enzymes, particularly serine proteases, due to its specific cleavage site. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers engaged in enzyme kinetics, inhibitor screening, and biochemical pathway analysis.

Application

• Enzyme Activity Assays: As a chromogenic substrate for quantifying the activity of specific proteases like dipeptidyl peptidase IV (DPP-IV) and related enzymes.
• Biochemical Research: For studying enzyme kinetics, inhibition mechanisms, and substrate specificity in academic and industrial laboratories.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential therapeutic enzyme inhibitors.
• Diagnostic Development: A key component in the formulation of clinical diagnostic kits for measuring specific enzyme levels in biological samples.
• Quality Control in Bioprocessing: Monitoring protease activity during the production and purification of biopharmaceuticals.

Basic Information

Product Name	Suc-Ala-Pro-Ala-Pna
CAS No.	72682-79-2
Molecular Formula	C23H31N5O8
Molecular Weight	505.52 g/mol
Synonyms	Suc-Ala-Pro-Ala-p-nitroanilide; N-Succinyl-Ala-Pro-Ala-p-nitroanilide; Suc-APA-pNA; Suc-Ala-Pro-Ala-pNA; Substrate for DPP-IV; Chromogenic Peptide Substrate; N-Succinyl-Alanyl-Prolyl-Alanyl-p-nitroanilide; Alanylprolylalanine 4-nitroanilide deriv.
EINECS	Contact for details

Quality Control

Our Suc-Ala-Pro-Ala-Pna is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and verification of performance in functional assays. Certificates of Analysis (COA) detailing purity, identity, and assay results are provided to ensure reproducibility and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Tested in standard enzymatic assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.