Description

Suc-Ala-Ala-Pro-Val-Pna is a specialized chromogenic peptide substrate designed for enzymatic activity assays. This compound is critical for researchers and quality control laboratories requiring precise, spectrophotometric detection of protease activity. It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic industries for enzyme kinetics studies, inhibitor screening, and assay development.

Application

• Protease Activity Assays: As a specific chromogenic substrate for measuring the activity of enzymes like elastase and related serine proteases.
• Enzyme Kinetics & Inhibition Studies: Used in high-throughput screening (HTS) platforms to determine kinetic parameters (Km, Vmax) and evaluate potential enzyme inhibitors.
• Diagnostic Reagent Development: A key component in the formulation of diagnostic kits for detecting protease levels relevant to certain disease states.
• Biochemical Research: Employed in academic and industrial R&D for studying protease function, substrate specificity, and catalytic mechanisms.
• Pharmaceutical Quality Control: Used in QC labs to monitor the activity and consistency of enzyme-based biopharmaceutical products during manufacturing.

Basic Information

Product Name	Suc-Ala-Ala-Pro-Val-Pna
CAS No.	72682-76-9
Molecular Formula	C27H38N6O8
Molecular Weight	574.63 g/mol
Synonyms	Suc-AAPV-pNA; N-Succinyl-Ala-Ala-Pro-Val p-nitroanilide; Suc-Ala-Ala-Pro-Val-4-nitroanilide; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-valine 4-nitroanilide; Suc-AAPV-NA; Elastase Substrate IV; Chromogenic Elastase Substrate; Suc-(Ala)2-Pro-Val-pNA
EINECS	Contact for details

Quality Control

Our Suc-Ala-Ala-Pro-Val-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.