Description

S-(2-Phenyl-2-Hydroxyethyl)Glutathione is a specialized, synthetically derived glutathione conjugate, a key intermediate in the study of detoxification pathways and oxidative stress mechanisms. This compound is of significant value in biochemical and pharmaceutical research for its role in modeling metabolic conjugation reactions and investigating enzyme kinetics. It is primarily needed by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity biochemical reagents focused on advanced metabolic studies and drug discovery.

Application

• Biochemical Research: Used as a critical reference standard and substrate in enzymatic studies related to glutathione S-transferase (GST) activity and conjugation pathways.
• Pharmaceutical Development: Serves as an important intermediate in the synthesis and metabolic profiling of novel drug candidates, particularly those undergoing Phase I detoxification.
• Toxicology Studies: Employed in in vitro and in vivo models to investigate cellular defense mechanisms against electrophilic toxins and reactive oxygen species.
• Diagnostic Reagent Manufacturing: A key component in the formulation of high-sensitivity assay kits for measuring glutathione-related enzyme functions.
• Nutraceutical Research: Used in advanced studies exploring the bioavailability and novel conjugated forms of glutathione for potential therapeutic applications.
• Academic Research: A valuable tool for universities and research institutes studying redox biology, metabolic engineering, and the biochemical basis of disease.

Basic Information

Product Name	S-(2-Phenyl-2-Hydroxyethyl)Glutathione
CAS No.	72616-33-2
Molecular Formula	C18H27N3O7S
Molecular Weight	429.49 g/mol
Synonyms	Glutathione S-(2-phenyl-2-hydroxyethyl) ester; S-(2-Hydroxy-2-phenylethyl)glutathione; 2-Phenyl-2-hydroxyethyl glutathione thioether; L-Glutathione, S-(2-hydroxy-2-phenylethyl)-; γ-Glu-Cys-Gly S-(2-phenyl-2-hydroxyethyl) conjugate; NSC 339587; GSH Phenylethyl Hydroxy Conjugate
EINECS	Contact for details

Quality Control

Our S-(2-Phenyl-2-Hydroxyethyl)Glutathione is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.