Description

3,5-Dibr-Tyr1-Methionine Enkephalin is a synthetic, halogenated analog of the endogenous opioid peptide methionine-enkephalin. This modified peptide is a critical research tool for studying opioid receptor pharmacology, structure-activity relationships, and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neuroscience and pain management.

Application

• Neuroscience Research: A key ligand for investigating the binding affinity, selectivity, and functional activity of delta (δ) and mu (μ) opioid receptor subtypes.
• Structure-Activity Relationship (SAR) Studies: Used to elucidate the role of specific amino acid residues, particularly tyrosine halogenation, in peptide-receptor interactions and biological potency.
• Biochemical Assay Development: Serves as a reference standard or competitor in receptor binding assays, cAMP accumulation tests, and other in vitro pharmacological screenings.
• Peptide Chemistry & Drug Discovery: Acts as a synthetic intermediate or a template for designing novel peptide-based analgesics with potentially improved metabolic stability or receptor profile.

Basic Information

Product Name	3,5-Dibr-Tyr1-Methionine Enkephalin
CAS No.	72601-99-1
Molecular Formula	C32H41Br2N5O7S
Molecular Weight	791.58 g/mol
Synonyms	[Dibromotyrosine1]-Methionine Enkephalin; 3,5-Dibromo-Tyr1-Met-Enkephalin; Tyr(3,5-Br2)-Gly-Gly-Phe-Met; H-Tyr(3,5-Br2)-Gly-Gly-Phe-Met-OH; 3,5-Dibromotyrosyl-glycyl-glycyl-phenylalanyl-methionine; Opioid Peptide Analog; Brominated Enkephalin
EINECS	Contact for details

Quality Control

Our 3,5-Dibr-Tyr1-Methionine Enkephalin is manufactured under strict quality systems. Each batch is characterized and tested to ensure identity, purity, and consistency suitable for advanced research applications. Comprehensive analytical data, including HPLC purity, MS confirmation, and amino acid analysis, are documented in the batch-specific Certificate of Analysis (COA), which is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Single Impurity (HPLC)	≤1.0%
Water Content (KF)	≤5.0%
Peptide Content	≥80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.