Description

3,5-Dibr-Tyr1 Leucine Enkephalin is a synthetic, modified peptide analog of the endogenous opioid peptide leucine enkephalin. This compound is of significant value in biochemical and pharmacological research due to its role as a potent and selective ligand for studying delta opioid receptor (DOR) interactions and signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, pain management research, and the development of novel therapeutic agents targeting the opioid system.

Application

• Neuroscience Research: A critical tool for investigating the function and distribution of delta opioid receptors in the central nervous system.
• Pharmacological Studies: Used in receptor binding assays and functional studies to evaluate agonist/antagonist activity and signal transduction mechanisms.
• Pain Research: Serves as a reference compound in studies aimed at understanding the endogenous opioid system's role in analgesia and developing non-addictive pain relievers.
• Biochemical Standard: Employed as a high-purity standard for analytical method development and validation in peptide analysis.
• Drug Discovery: Used as a lead compound or structural template in medicinal chemistry programs for designing new opioid receptor modulators.

Basic Information

Product Name	3,5-Dibr-Tyr1 Leucine Enkephalin
CAS No.	72601-98-0
Molecular Formula	C34H46Br2N6O8
Molecular Weight	818.58 g/mol
Synonyms	[D-Ala2, 3,5-Dibromo-Tyr1, Leu5]-Enkephalin; 3,5-Dibromo-Tyrosine1-Leucine Enkephalin; H-Tyr(3,5-Br2)-D-Ala-Gly-Phe-Leu-OH; DADLE analog; Delta opioid receptor selective agonist; Tyr(3,5-Br2)-D-Ala-Gly-Phe-Leu; 3,5-Dibromotyrosyl-d-alanylglycyl-phenylalanyl-leucine
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dibr-Tyr1 Leucine Enkephalin is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency suitable for advanced research applications. Our quality assurance includes comprehensive analytical characterization using HPLC, MS, and NMR. A Certificate of Analysis (COA) detailing purity, related substances, and analytical data is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.