Description

2-Amino-3-(5-Hydroxy-1H-Indol-3-Yl)Propanoic Acid is a specialized indole derivative and a non-proteinogenic amino acid of significant interest in biochemical research and pharmaceutical development. Its unique structure, featuring both an indole and a phenolic hydroxyl group, makes it a valuable precursor and building block for synthesizing complex bioactive molecules. This compound is primarily sought by research institutions and pharmaceutical companies engaged in neuroscience, metabolic studies, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Biochemical Research: Used as a reference standard and a precursor in studies of tryptophan metabolism, serotonin pathways, and the biosynthesis of related alkaloids.
• Neuroscience Studies: Employed in the research of neurotransmitter analogs and modulators due to its structural similarity to endogenous signaling molecules.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships (SAR) and to create peptides with enhanced biological properties.
• Enzyme Substrate/Analog: Serves as a substrate or inhibitor in enzymatic assays for research on amino acid decarboxylases and hydroxylases.
• Chemical Biology Probes: Utilized in the development of molecular probes for labeling and studying biological systems.

Basic Information

Product Name	2-Amino-3-(5-Hydroxy-1H-Indol-3-Yl)Propanoic Acid
CAS No.	72572-98-6
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	5-Hydroxytryptophan, 5-HTP; L-5-Hydroxytryptophan; 3-(5-Hydroxy-1H-indol-3-yl)-L-alanine; Oxitriptan; 5-Hydroxy-L-tryptophan; 5-Hydroxy-L-α-tryptophan; 5-HTP; L-5-HTP
EINECS	Contact for details

Quality Control

Our 2-Amino-3-(5-Hydroxy-1H-Indol-3-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming compliance with in-house specifications. We support cGMP-grade production for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.