Description

1-[2-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine is a specialized aromatic amine derivative featuring both chloro and trifluoromethyl substituents, making it a valuable chiral building block and intermediate in advanced synthesis. This compound matters for its role in creating complex molecules with enhanced biological activity and physicochemical properties. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive for specialty polymers and advanced organic materials.
• Chemical Reference Standard: Supplied to analytical laboratories for method development, calibration, and quality control testing.

Basic Information

Product Name	1-[2-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine
CAS No.	72561-45-6
Molecular Formula	C9H7ClF3N
Molecular Weight	221.60 g/mol
Synonyms	1-(2-Chloro-3-(trifluoromethyl)phenyl)ethanamine; α-Methyl-2-chloro-3-(trifluoromethyl)benzylamine; 2-Chloro-α-methyl-3-(trifluoromethyl)benzylamine; 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethylamine; (RS)-1-[2-Chloro-3-(trifluoromethyl)phenyl]ethanamine; 72561-45-6; Benzeneethanamine, 2-chloro-α-methyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-[2-Chloro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.