Description

Benzenemethanol, 3-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci) CAS NO 72522-42-0 is a high-purity, chiral fluorinated benzenemethanol derivative, distinguished by its nitro and trifluoromethyl substituents. This compound is a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control for complex molecule construction. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced, optically active pesticides and herbicides where the specific stereochemistry influences biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that incorporate nitro and trifluoromethyl functional groups.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including novel fluorination and cross-coupling reactions.

Basic Information

Product Name	Benzenemethanol, 3-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci)
CAS No.	72522-42-0
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	(S)-α-(Trifluoromethyl)-3-nitrobenzenemethanol; (S)-3-Nitro-α-(trifluoromethyl)benzyl alcohol; (S)-1-(3-Nitrophenyl)-2,2,2-trifluoroethanol; (S)-Nitro-α-trifluoromethylbenzyl alcohol; (S)-NTFB Alcohol; 3-Nitro-α-(trifluoromethyl)benzyl alcohol, (S)-; (S)-1-(3-Nitrophenyl)-2,2,2-trifluoroethan-1-ol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 3-Nitro-α-(Trifluoromethyl)-, (S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.