Description

2-Amino-n-(1-Benzyl-3-Pyrrolidinyl)-4-Methoxy-5-Pyrimidinecarboxamide Oxalate is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant pharmaceutical importance. This compound is a critical building block in the research and development of novel antiviral therapeutics, particularly for the treatment of HIV. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis facilities, and contract manufacturing organizations (CMOs) focused on advanced antiviral drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of non-nucleoside reverse transcriptase inhibitor (NNRTI) class antiviral drugs.
• Antiviral Drug Research: Serves as a core scaffold for the discovery and development of new therapeutic agents targeting HIV and other retroviruses.
• Biochemical Research: Used in enzymatic and binding studies to understand the mechanism of action of reverse transcriptase inhibition.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, biologically active molecules in medicinal chemistry.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation of related pharmaceutical products.

Basic Information

Product Name	2-Amino-n-(1-Benzyl-3-Pyrrolidinyl)-4-Methoxy-5-Pyrimidinecarboxamide Oxalate
CAS No.	72412-41-0
Molecular Formula	C₁₈H₂₃N₅O₃ • C₂H₂O₄
Molecular Weight	457.46 g/mol
Synonyms	2-Amino-N-[1-benzyl-3-pyrrolidinyl]-4-methoxy-5-pyrimidinecarboxamide oxalate; Delavirdine Mesylate Intermediate; U-90152S Intermediate; BHAP Derivative; 5-Pyrimidinecarboxamide, 2-amino-N-[1-(phenylmethyl)-3-pyrrolidinyl]-4-methoxy-, (2E)-2-butenedioate (1:1); NSC 339768; 1-(1-Benzyl-3-pyrrolidinyl)-2-amino-4-methoxy-5-pyrimidinecarboxamide oxalate
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(1-Benzyl-3-Pyrrolidinyl)-4-Methoxy-5-Pyrimidinecarboxamide Oxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.