Description

4-Fluorophenyl Methanesulfonate is a versatile and high-purity chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a key building block for introducing the 4-fluorophenyl moiety into more complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of modern pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Acts as a monomer or modifying agent in the creation of specialty polymers and advanced materials with specific electronic or surface properties.
• Liquid Crystal & OLED Development: Employed in the synthesis of fluorinated components for display and lighting technologies.
• Cross-Coupling Reactions: Functions as an effective electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Protecting Group Chemistry: Can be utilized in multi-step synthetic routes where selective protection and deprotection of functional groups are required.

Basic Information

Product Name	4-Fluorophenyl Methanesulfonate
CAS No.	72358-72-6
Molecular Formula	C8H9FO3S
Molecular Weight	204.22 g/mol
Synonyms	4-Fluorophenyl Mesylate; p-Fluorophenyl Methanesulfonate; Methanesulfonic Acid 4-Fluorophenyl Ester; 4-Fluoro-1-methanesulfonyloxybenzene; 1-Fluoro-4-(methylsulfonyloxy)benzene; 4-Fluorophenyl Methyl Sulfonate; (4-Fluorophenyl) Methanesulfonate; 4-Fluoro Phenyl Mesylate
EINECS	Contact for details

Quality Control

Our 4-Fluorophenyl Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.