Description

5-Bromo-2,4-Dimethylbenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, versatile sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group to create novel compounds with specific properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require a reliable, high-quality reagent for developing active ingredients and functional materials. The compound is supplied in its free form, ensuring optimal reactivity and compatibility in sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the sulfonyl moiety imparts specific biological activity.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and liquid crystals that require sulfonated structures for enhanced performance.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling and modifying biomolecules in research applications.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed coupling reactions to construct complex aromatic systems.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2,4-Dimethylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	72256-96-3
Molecular Formula	C8H8BrClO2S
Molecular Weight	283.57 g/mol
Synonyms	2,4-Dimethyl-5-bromobenzenesulfonyl chloride; 5-Bromo-2,4-dimethylbenzene-1-sulfonyl chloride; 1-Bromo-2,4-dimethyl-5-sulfonylchloridebenzene; Benzenesulfonyl chloride, 5-bromo-2,4-dimethyl-; 5-Bromo-2,4-dimethylphenylsulfonyl chloride; 5-Bromo-2,4-dimethylbenzenesulphonyl chloride; 72256-96-3 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Dimethylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.