Description

4-Bromo-3-Methylbenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound, serving as a critical sulfonylation reagent and a key synthetic intermediate in advanced organic synthesis. Its primary value lies in its ability to introduce the sulfonyl chloride functional group into target molecules, enabling the construction of complex sulfonamides and sulfonate esters. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery, active ingredient development, and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based drugs with potential therapeutic applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the sulfonyl moiety can confer specific biological activity.
• Dye and Pigment Manufacturing: Serves as an intermediate in the production of specialty dyes and organic pigments, contributing to color fastness and molecular stability.
• Polymer Chemistry: Employed in the modification of polymers and the synthesis of specialty monomers to impart specific chemical resistance or functional properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.

Basic Information

Product Name	4-Bromo-3-Methylbenzenesulfonyl Chloride
CAS No.	72256-93-0
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	3-Methyl-4-bromobenzenesulfonyl chloride; 4-Bromo-m-toluenesulfonyl chloride; 1-Bromo-2-methyl-5-(chlorosulfonyl)benzene; 2-Methyl-5-bromobenzenesulfonyl chloride; p-Bromo-m-toluenesulfonyl chloride; 5-Bromo-2-methylbenzenesulfonyl chloride; 4-Bromo-3-methylphenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Methylbenzenesulfonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles to meet the exacting standards of our global B2B clients in research and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.