Description

3,4-Difluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity of the benzylamine group combined with the electronic effects imparted by the difluoro substitution pattern on the aromatic ring. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and advanced materials with tailored properties.
• Liquid Crystal and OLED Materials: A building block for fluorinated components in electronic display technologies and organic light-emitting diodes.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reaction methodologies and creating compound libraries for screening.

Basic Information

Product Name	3,4-Difluorobenzylamine
CAS No.	72235-53-1
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	(3,4-Difluorophenyl)methanamine; 1-(Aminomethyl)-3,4-difluorobenzene; 3,4-Difluorobenzyl amine; Benzenemethanamine, 3,4-difluoro-; 3,4-DFBA; α-Amino-3,4-difluorotoluene
EINECS	Contact for details

Quality Control

Our 3,4-Difluorobenzylamine is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.