Description

2,3-Difluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzylamine core, which can dramatically alter the electronic properties, metabolic stability, and binding affinity of final target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where the difluoro motif enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Intermediate in the synthesis of fluorinated polymers, liquid crystals, and electronic chemicals.
• Custom Synthesis and R&D: Serves as a starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring structure-activity relationships (SAR) in fluorinated molecules.

Basic Information

Product Name	2,3-Difluorobenzylamine
CAS No.	72235-51-9
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	(2,3-Difluorophenyl)methanamine; 1-(2,3-Difluorophenyl)methanamine; 2,3-Difluorobenzyl amine; 2,3-Difluoro-α-toluidine; Benzenemethanamine, 2,3-difluoro-; 2,3-DFBA; α-Amino-2,3-difluorotoluene
EINECS	Contact for details

Quality Control

Our 2,3-Difluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.