Description

Thromboplastin From Rabbit Brain, 1 X 40 Mg is a high-purity, lyophilized tissue factor preparation derived from rabbit brain, serving as a critical reagent in coagulation diagnostics. This product is essential for the accurate and reliable determination of prothrombin time (PT), a fundamental test for assessing the extrinsic pathway of blood coagulation. It is primarily utilized by clinical diagnostics laboratories, pharmaceutical R&D departments, and quality control units in the biopharmaceutical industry for research, in-vitro diagnostics, and hemostasis monitoring.

Application

• Prothrombin Time (PT) Testing: The primary application is as the key reagent in PT assays for evaluating the extrinsic and common coagulation pathways in clinical diagnostics.
• Coagulation Factor Assays: Used in the quantitative determination of specific clotting factors (e.g., Factor II, V, VII, X) for diagnosing coagulation disorders.
• Anticoagulant Therapy Monitoring: Critical for monitoring the efficacy of oral anticoagulant therapies like warfarin, ensuring patient safety and therapeutic effectiveness.
• In-Vitro Diagnostic (IVD) Manufacturing: A key raw material in the production of diagnostic kits, calibrators, and controls for hemostasis testing systems.
• Biomedical Research: Employed in research studies investigating blood coagulation mechanisms, thrombus formation, and the development of new antithrombotic agents.
• Quality Control in Pharmaceutical Production: Used to test for the presence of procoagulant contaminants in biological products like vaccines and therapeutic proteins.

Basic Information

Item	Details
Product Name	Thromboplastin From Rabbit Brain, 1 X 40 Mg
CAS No.	72162-96-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Thromboplastin; Brain Thromboplastin; Tissue Factor (Rabbit Brain); Coagulation Factor III; Rabbit Brain Extract; PT Reagent; Prothrombin Time Reagent; Tromboplastina
EINECS	Contact for details

Quality Control

Our Thromboplastin From Rabbit Brain is manufactured under stringent conditions to ensure batch-to-batch consistency and performance. Each lot undergoes rigorous quality testing, including activity assays, sensitivity to anticoagulants, and stability testing, to ensure it meets the high standards required for diagnostic and research applications. Certificates of Analysis (COA) detailing purity, activity (ISI value where applicable), and specifications are available upon request.

Storage

Preserve in the original tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	Lyophilized powder or cake
Identification	Conforms (Functional Activity)
Activity (PT Clotting Time)	Within specified range for control plasma
International Sensitivity Index (ISI)	Lot-specific value provided (where applicable)
Moisture Content	≤ 3.0% (by loss on drying)
Reconstitution Stability	Stable for specified period at 2-8°C
Biological Safety (Sterility/Endotoxin)	Tested and controlled

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.