Description

Somatostatin, Cyclic Hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- CAS NO 72127-61-8 is a synthetic cyclic hexapeptide analog of the endogenous hormone somatostatin. This compound is valued for its potent biological activity and high binding affinity to somatostatin receptors, making it a critical tool in endocrine research and drug discovery. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on metabolic disorders, neuroendocrinology, and oncology.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel therapeutics targeting somatostatin receptors.
• Endocrinology Studies: Used in vitro and in vivo to study the inhibition of growth hormone, insulin, and glucagon secretion.
• Oncology Research: Investigated for its potential anti-proliferative effects on various cancer cell lines, particularly neuroendocrine tumors.
• Biochemical Assay Development: Employed as a ligand in receptor binding assays (RBA) and for the calibration of analytical methods like HPLC and LC-MS.
• Peptide Chemistry & Conjugation: Acts as a model compound for studying cyclic peptide stability, structure-activity relationships (SAR), and conjugation techniques.
• Veterinary Medicine: Potential applications in animal health research for metabolic and hormonal regulation.

Basic Information

Product Name	Somatostatin, Cyclic Hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- CAS NO 72127-61-8
CAS No.	72127-61-8
Molecular Formula	C47H56N10O8
Molecular Weight	888.99 g/mol
Synonyms	Cyclo(Phe-Phe-Trp-Lys-Thr-Phe); Cyclic Somatostatin Hexapeptide; Somatostatin (6-11) cyclic; H-Cys-Phe-Phe-Trp-Lys-Thr-Phe-Cys-OH (cyclic disulfide); L-Cysteine, L-phenylalanyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-threonyl-L-phenylalanyl-, cyclic (1→6)-disulfide; SRIF-14 (6-11) cyclic peptide; Somatostatin cyclic hexapeptide fragment
EINECS	Contact for details

Quality Control

Our Somatostatin, Cyclic Hexapeptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide Certificates of Analysis (COA) with detailed specifications for traceability and compliance. Our quality commitment ensures the material is suitable for research and development applications requiring high-purity peptides.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.