Description

L-3-Benzothienylalanine is a non-proteinogenic amino acid derivative featuring a benzothiophene side chain, offering unique steric and electronic properties. This compound is a critical chiral building block in medicinal chemistry, valued for its role in modulating peptide conformation and biological activity. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel therapeutic agents, including enzyme inhibitors and peptide-based drugs.

Application

• Pharmaceutical Intermediates: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Peptidomimetics: Used to incorporate constrained, aromatic amino acid analogs into peptide chains to enhance stability and receptor binding affinity.
• Protease & Kinase Inhibitors: Serves as a core structural component in the design of small-molecule inhibitors targeting specific enzymes.
• Chemical Biology Probes: Employed in the synthesis of labeled or tagged compounds for studying biological pathways and protein function.
• Academic & Contract Research: Used in university and CRO laboratories for exploratory synthetic chemistry and drug discovery projects.
• Custom Synthesis: A starting material for the tailored production of complex, high-value specialty chemicals.

Basic Information

Product Name	L-3-Benzothienylalanine
CAS No.	72120-71-9
Molecular Formula	C11H11NO2S
Molecular Weight	221.27 g/mol
Synonyms	(S)-2-Amino-3-(benzo[b]thiophen-3-yl)propanoic acid; L-3-(2-Benzothienyl)alanine; 3-Benzothienyl-L-alanine; (S)-3-(Benzothiophen-3-yl)alanine; BTA; 72120-71-9; L-BTA
EINECS	Contact for details

Quality Control

Our L-3-Benzothienylalanine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing specific results for identity, assay, chiral purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.