Description

Tuftsin Acetate Salt is a synthetic, biologically active peptide derivative of the natural immunostimulant tuftsin. This compound is significant for its role in modulating and enhancing immune system responses, particularly macrophage and leukocyte activity. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing immunotherapies, vaccine adjuvants, and as a critical reagent in immunological studies.

Application

• Immunotherapy Research: Investigated as a potential agent for stimulating the immune system against infections and certain cancers.
• Vaccine Adjuvant Development: Used in preclinical studies to enhance the efficacy of vaccines by boosting cellular immune responses.
• Biochemical Research: Serves as a standard or reference compound in studies of phagocytosis, leukocyte chemotaxis, and macrophage activation.
• Pharmaceutical Intermediates: Acts as a key building block or active pharmaceutical ingredient (API) in the synthesis of novel immunomodulatory drugs.
• Cell Culture & In Vitro Studies: Employed in laboratory settings to study its effects on immune cell lines and primary cell cultures.

Basic Information

Product Name	Tuftsin Acetate Salt
CAS No.	72103-53-8
Molecular Formula	C27H44N8O9 • xC2H4O2
Molecular Weight	624.70 g/mol (Free base)
Synonyms	L-Threonyl-L-Lysyl-L-Prolyl-L-Arginine Acetate Salt; Thr-Lys-Pro-Arg Acetate; Tuftsin (human) acetate; Immunostimulant Peptide TP Acetate; Tuftsin Fragment 289-292 Acetate; H-Thr-Lys-Pro-Arg-OH acetate; RPKP Acetate Salt
EINECS	Contact for details

Quality Control

Our Tuftsin Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for residual solvents and endotoxins where applicable. A Certificate of Analysis (COA) detailing all specifications is provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Acetate Content (IC)	5.0% - 12.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.