Description

n-Acetyl-S-(3-Chloroprop-2-Enyl)Cysteine is a specialized cysteine derivative featuring an acetyl-protected thiol group and a reactive chloropropenyl moiety. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents and biochemical research tools, valued for its role in introducing sulfhydryl functionality and enabling specific conjugation chemistries. It is primarily utilized by research institutions and pharmaceutical development companies engaged in drug discovery, proteomics, and the synthesis of targeted covalent inhibitors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those designed as covalent enzyme inhibitors.
• Bioconjugation Reagent: Used in the modification of peptides, proteins, and antibodies to introduce specific functional handles or for site-specific labeling.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies, particularly those investigating cysteine metabolism and detoxification pathways.
• Proteomics Tool: Employed in the development of activity-based probes (ABPs) for profiling enzyme activities within complex biological samples.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with unique thiol-ene reactivity.

Basic Information

Product Name	n-Acetyl-S-(3-Chloroprop-2-Enyl)Cysteine
CAS No.	72072-41-4
Molecular Formula	C8H12ClNO3S
Molecular Weight	237.70 g/mol
Synonyms	N-Acetyl-S-(3-chloro-2-propen-1-yl)-L-cysteine; S-(3-Chloro-2-propenyl)-N-acetylcysteine; 3-Chloroallylmercapturic Acid; N-Acetyl-S-(3-chloroallyl)cysteine; Mercapturic Acid of 3-Chloroallyl Chloride; 1-(Acetylamino)-2-[(3-chloro-2-propen-1-yl)sulfanyl]carbonylethane; L-Cysteine, N-acetyl-S-(3-chloro-2-propen-1-yl)-; ACETYL-S-(3-CHLOROPROP-2-ENYL)CYSTEINE
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(3-Chloroprop-2-Enyl)Cysteine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.