Description

(+)-Biotin-ε-Aminocaproic Acid is a high-purity, chemically modified derivative of biotin, designed for advanced bioconjugation and targeted delivery applications. This compound is critical for researchers and manufacturers requiring precise, stable linkages between biotin and biomolecules or surfaces. It is primarily utilized in the pharmaceutical, diagnostic, and life science research sectors for developing novel therapeutics, diagnostic assays, and affinity purification systems.

Application

• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of targeted drug conjugates and antibody-drug conjugates (ADCs).
• Diagnostic Reagent Manufacturing: Used to create biotinylated probes and labels for ELISA, lateral flow assays, and other immunoassay platforms.
• Affinity Chromatography Media: Functionalized onto resins or surfaces for the purification of streptavidin/avidin-tagged proteins.
• Bioconjugation & Linker Chemistry: The ε-aminocaproic acid spacer arm provides flexibility and reduces steric hindrance in biotin-streptavidin binding.
• Life Science Research: Essential tool for cell surface labeling, pull-down assays, and molecular imaging studies.
• Nutraceutical & Cosmetic R&D: Investigated for advanced delivery systems in topical and nutritional formulations.

Basic Information

Product Name	(+)-Biotin-ε-Aminocaproic Acid
CAS No.	72040-64-3
Molecular Formula	C16H28N4O4S
Molecular Weight	372.48 g/mol
Synonyms	Biotin-6-aminocaproic acid; Biotin-ε-aminocaproic acid; N-Biotinyl-6-aminocaproic acid; D-Biotinyl-ε-aminocaproic acid; (+)-Biotinyl-6-aminohexanoic acid; Biotin-ACA; Biotin-C6-COOH; Biotinyl-ε-Ahx-OH
EINECS	Contact for details

Quality Control

Our (+)-Biotin-ε-Aminocaproic Acid CAS NO 72040-64-3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: +45° to +55° (c=1 in DMSO)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.