Description

Nalpha-Fmoc-L-Asparagine is a protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). Its primary value lies in providing a reactive α-amino group protected by the base-labile 9-fluorenylmethoxycarbonyl (Fmoc) group, while the side chain amide of asparagine remains unprotected, allowing for selective deprotection and chain elongation. This high-purity building block is critical for researchers and manufacturers in pharmaceutical development, biotechnology, and academic research who require reliable, consistent reagents for producing peptides, peptide hormones, and investigative biomolecules. CAS No. 71989-16-7.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediates: Used in the research and development of therapeutic peptides and peptidomimetics.
• Bioconjugation: Serves as a key component for linking peptides to other molecules, such as drugs, dyes, or polymers.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial Research: A standard reagent for studying protein structure-function relationships and biochemical pathways.
• Production of Diagnostic Reagents: Used in the synthesis of peptide antigens for immunoassays and diagnostic kits.

Basic Information

Product Name	Nalpha-Fmoc-L-Asparagine
CAS No.	71989-16-7
Molecular Formula	C19H18N2O5
Molecular Weight	354.36 g/mol
Synonyms	Fmoc-Asn-OH; Fmoc-L-Asparagine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-asparagine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]butanediamide; N-α-Fmoc-L-asparagine; Fmoc-Asparagine; N-Fmoc-L-asparagine; L-Asparagine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our Nalpha-Fmoc-L-Asparagine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurities is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.