Description

Tetrafluoroaniline is a high-purity fluorinated aromatic amine building block, essential for synthesizing advanced materials and active pharmaceutical ingredients. Its unique structure, featuring four fluorine atoms, imparts exceptional electron-withdrawing properties and stability, making it a critical intermediate for demanding applications. This compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms improve biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core building block for electron-transport materials and charge-generation layers in display and lighting technologies.
• Polymer Modification: Incorporated into high-performance polymers, such as polyimides and polyamides, to enhance thermal stability, chemical resistance, and dielectric properties.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes with unique color fastness and spectral properties.
• Cross-Coupling Reactions: Acts as a valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create complex biaryl structures.

Basic Information

Product Name	Tetrafluoroaniline
CAS No.	71964-99-3
Molecular Formula	C6H3F4N
Molecular Weight	165.09 g/mol
Synonyms	2,3,5,6-Tetrafluoroaniline; Perfluoroaniline; 1-Amino-2,3,5,6-tetrafluorobenzene; 2,3,5,6-Tetrafluorobenzenamine; Tetrafluorobenzene-1-amine; TFA; NSC 88431
EINECS	Contact for details

Quality Control

Our Tetrafluoroaniline is manufactured under a strict quality management system. Every batch is analyzed to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to ensure consistent quality and traceability for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.